Unterschiede

Hier werden die Unterschiede zwischen zwei Versionen angezeigt.

--- genetik:gelbes_fett_bco2 [2026/11/01 10:37] – [Verbreitung der delAAT-Variante] kathrin
+++ genetik:gelbes_fett_bco2 [2026/11/01 21:13] (aktuell) – kathrin
@@ Zeile 13: / Zeile 13: @@
 ^ ^DNA^Protein^::: ^::: ^::: ^
 |Y, ins |Wildtyp | |Katalyse der oxydativen Spaltung von Carotinoiden |Weißes Fettgewebe bei ins/ins oder ins/del((Strychalski, J., Brym, P., Czarnik, U., & Gugołek, A. (2015). A novel AAT-deletion mutation in the coding sequence of the BCO2 gene in yellow-fat rabbits. Journal of applied genetics, 56(4), 535-537.))((Strychalski, J., Gugołek, A., Brym, P., Antoszkiewicz, Z., & Chwastowska-Siwiecka, I. 2019. Polymorphism of the BCO2 gene and the content of carotenoids, retinol, and α-tocopherol in the liver and fat of rabbits. Revista Brasileira de Zootecnia, 48, e20180243.)) | |
-|y, del |AAT //In-frame//-Deletion, Codon 248, Exon 6((Strychalski, J., Brym, P., Czarnik, U., & Gugołek, A. (2015). A novel AAT-deletion mutation in the coding sequence of the BCO2 gene in yellow-fat rabbits. Journal of applied genetics, 56(4), 535-537.))((Strychalski, J., Gugołek, A., Brym, P., Antoszkiewicz, Z., & Chwastowska-Siwiecka, I. 2019. Polymorphism of the BCO2 gene and the content of carotenoids, retinol, and α-tocopherol in the liver and fat of rabbits. Revista Brasileira de Zootecnia, 48, e20180243.)) |Fehlen der Aminosäure Asparagin|Gestörter Carotinoid-Stoffwechsel |Anreicherung von [[naehrstoffe:fett|Carotinoiden aus der Nahrung]], insbesondere Xanthophyllen, im Fettgewebe/ gelbes Fettgewebe bei del/del((Willimott, S. G. 1928. On the pigment of the fat of certain rabbits. Biochemical Journal, 22(4), 1057.))((Castle, W. E. 1933. The linkage relations of yellow fat in rabbits. Proceedings of the National Academy of Sciences, 19(11), 947-950.))((Strychalski, J., Brym, P., Czarnik, U., & Gugołek, A. (2015). A novel AAT-deletion mutation in the coding sequence of the BCO2 gene in yellow-fat rabbits. Journal of applied genetics, 56(4), 535-537.))((Strychalski, J., Gugołek, A., Brym, P., Antoszkiewicz, Z., & Chwastowska-Siwiecka, I. 2019. Polymorphism of the BCO2 gene and the content of carotenoids, retinol, and α-tocopherol in the liver and fat of rabbits. Revista Brasileira de Zootecnia, 48, e20180243.)) (mögliche ernährungsphysiologische Vorteile des Fleischs durch höhere Nährstoffgehalte, ohne bedeutende Nachteile fürs Tier) |//Flemish Giants// und Kreuzungen((Castle, W. E. 1929. The rex rabbit. Journal of Heredity, 20(5), 193-199.)); Kreuzungen((Castle, W. E. 1933. The linkage relations of yellow fat in rabbits. Proceedings of the National Academy of Sciences, 19(11), 947-950.)); //Flemish Giant, New Zealand Red//((Strychalski, J., Brym, P., Czarnik, U., & Gugołek, A. (2015). A novel AAT-deletion mutation in the coding sequence of the BCO2 gene in yellow-fat rabbits. Journal of applied genetics, 56(4), 535-537.)); Kreuzungen von //Flemish Giant//, //New Zealand Red// und //Termond White// (Polen)((Strychalski, J., Gugołek, A., Brym, P., Antoszkiewicz, Z., & Chwastowska-Siwiecka, I. 2019. Polymorphism of the BCO2 gene and the content of carotenoids, retinol, and α-tocopherol in the liver and fat of rabbits. Revista Brasileira de Zootecnia, 48, e20180243.)); weitere((Taurisano, V., Ribani, A., Bovo, S., Schiavo, G., Bertolini, F., Schiavitto, M., & Fontanesi, L. 2025. Frequency of the beta-carotene oxygenase 2 (BCO2) allele associated with the yellow fat phenotype in rabbits: insights into the spread of a genetic alteration in a wide variety of breeds and populations. Livestock Science, 105842. https://doi.org/10.1016/j.livsci.2025.105842)) |
+|y, del |AAT //In-frame//-Deletion, Codon 248, Exon 6((Strychalski, J., Brym, P., Czarnik, U., & Gugołek, A. (2015). A novel AAT-deletion mutation in the coding sequence of the BCO2 gene in yellow-fat rabbits. Journal of applied genetics, 56(4), 535-537.))((Strychalski, J., Gugołek, A., Brym, P., Antoszkiewicz, Z., & Chwastowska-Siwiecka, I. 2019. Polymorphism of the BCO2 gene and the content of carotenoids, retinol, and α-tocopherol in the liver and fat of rabbits. Revista Brasileira de Zootecnia, 48, e20180243.))((Strychalski, J., Gugołek, A., Brym, P., & Antoszkiewicz, Z. (2019). Effect of the β‐carotene oxygenase 2 genotype on the content of carotenoids, retinol and α‐tocopherol in the liver, fat and milk of rabbit does, reproduction parameters and kitten growth. Journal of animal physiology and animal nutrition, 103(5), 1585-1593.)) |Fehlen der Aminosäure Asparagin|Gestörter Carotinoid-Stoffwechsel |Anreicherung von [[naehrstoffe:fett|Carotinoiden aus der Nahrung]], insbesondere Xanthophyllen, im Fettgewebe/ gelbes Fettgewebe bei del/del((Willimott, S. G. 1928. On the pigment of the fat of certain rabbits. Biochemical Journal, 22(4), 1057.))((Castle, W. E. 1933. The linkage relations of yellow fat in rabbits. Proceedings of the National Academy of Sciences, 19(11), 947-950.))((Strychalski, J., Brym, P., Czarnik, U., & Gugołek, A. (2015). A novel AAT-deletion mutation in the coding sequence of the BCO2 gene in yellow-fat rabbits. Journal of applied genetics, 56(4), 535-537.)) (mögliche ernährungsphysiologische Vorteile des Fleischs durch höhere Nährstoffgehalte, ohne bedeutende Nachteile fürs Tier((Strychalski, J., Gugołek, A., Brym, P., Antoszkiewicz, Z., & Chwastowska-Siwiecka, I. 2019. Polymorphism of the BCO2 gene and the content of carotenoids, retinol, and α-tocopherol in the liver and fat of rabbits. Revista Brasileira de Zootecnia, 48, e20180243.))((Strychalski, J., Gugołek, A., Brym, P., & Antoszkiewicz, Z. (2019). Effect of the β‐carotene oxygenase 2 genotype on the content of carotenoids, retinol and α‐tocopherol in the liver, fat and milk of rabbit does, reproduction parameters and kitten growth. Journal of animal physiology and animal nutrition, 103(5), 1585-1593.))) |//Flemish Giants// und Kreuzungen((Castle, W. E. 1929. The rex rabbit. Journal of Heredity, 20(5), 193-199.)); Kreuzungen((Castle, W. E. 1933. The linkage relations of yellow fat in rabbits. Proceedings of the National Academy of Sciences, 19(11), 947-950.)); //Flemish Giant, New Zealand Red, Termond White// und deren Kreuzungen (Polen)((Strychalski, J., Brym, P., Czarnik, U., & Gugołek, A. (2015). A novel AAT-deletion mutation in the coding sequence of the BCO2 gene in yellow-fat rabbits. Journal of applied genetics, 56(4), 535-537.))((Strychalski, J., Gugołek, A., Brym, P., Antoszkiewicz, Z., & Chwastowska-Siwiecka, I. 2019. Polymorphism of the BCO2 gene and the content of carotenoids, retinol, and α-tocopherol in the liver and fat of rabbits. Revista Brasileira de Zootecnia, 48, e20180243.))((Strychalski, J., Gugołek, A., Brym, P., & Antoszkiewicz, Z. (2019). Effect of the β‐carotene oxygenase 2 genotype on the content of carotenoids, retinol and α‐tocopherol in the liver, fat and milk of rabbit does, reproduction parameters and kitten growth. Journal of animal physiology and animal nutrition, 103(5), 1585-1593.)); weitere((Taurisano, V., Ribani, A., Bovo, S., Schiavo, G., Bertolini, F., Schiavitto, M., & Fontanesi, L. 2025. Frequency of the beta-carotene oxygenase 2 (BCO2) allele associated with the yellow fat phenotype in rabbits: insights into the spread of a genetic alteration in a wide variety of breeds and populations. Livestock Science, 105842. https://doi.org/10.1016/j.livsci.2025.105842)) |
-Weiterführend:\\ Strychalski //et al//., 2022((Strychalski, J., Gugołek, A., Antoszkiewicz, Z., Fopp-Bayat, D., Kaczorek-Łukowska, E., Snarska, A., ... & Matusevičius, P. 2022. The effect of the BCO2 genotype on the expression of genes related to carotenoid, retinol, and α-tocopherol metabolism in rabbits fed a diet with aztec marigold flower extract. International Journal of Molecular Sciences, 23(18), 10552.))\\
+Weiterführend:\\ Wirkung des BCO2-Genotyps und eines dem Futter zugesetzten Pflanzenextrakts (Tagetes) auf die Expression von BCO1, BCO2, LRAT und TTPA in der Leber (Strychalski //et al//., 2022((Strychalski, J., Gugołek, A., Antoszkiewicz, Z., Fopp-Bayat, D., Kaczorek-Łukowska, E., Snarska, A., ... & Matusevičius, P. 2022. The effect of the BCO2 genotype on the expression of genes related to carotenoid, retinol, and α-tocopherol metabolism in rabbits fed a diet with aztec marigold flower extract. International Journal of Molecular Sciences, 23(18), 10552.))), im Fettgewebe und im Gehirn (Strychalski //et al//., 2023((Strychalski, J., Gugołek, A., Kaczorek-Łukowska, E., Antoszkiewicz, Z., & Matusevičius, P. 2023. The BCO2 Genotype and the Expression of BCO1, BCO2, LRAT, and TTPA Genes in the Adipose Tissue and Brain of Rabbits Fed a Diet with Marigold Flower Extract. International Journal of Molecular Sciences, 24(3), 2304.))).
-Strychalski //et al//., 2023((Strychalski, J., Gugołek, A., Kaczorek-Łukowska, E., Antoszkiewicz, Z., & Matusevičius, P. 2023. The BCO2 Genotype and the Expression of BCO1, BCO2, LRAT, and TTPA Genes in the Adipose Tissue and Brain of Rabbits Fed a Diet with Marigold Flower Extract. International Journal of Molecular Sciences, 24(3), 2304.))
 ===== Verbreitung der delAAT-Variante =====